The Eight Growth Factors Behind PRP Healing
PDGF, TGF-β, VEGF, EGF, FGF, IGF, KGF, CTGF — a plain-language guide to the signalling proteins that drive regeneration.
Platelets are far more than clotting cells. Stored inside their alpha granules is a reservoir of growth factors and bioactive proteins that, once released, orchestrate the body's tissue-healing process — attracting macrophages and mesenchymal stem cells to the site of injury.
PDGF (Platelet Derived Growth Factor) drives cell growth and the repair of blood vessels while stimulating collagen production. TGF-β (Transforming Growth Factor Beta) promotes the neogenesis of epithelial and vascular endothelial cells. VEGF (Vascular Endothelial Growth Factor) and EGF (Epidermal Growth Factor) both promote angiogenesis and wound healing.
FGF (Fibroblast Growth Factor) is active in the epithelialization phase, helping keratinocytes cover a wound. IGF (Insulin-like Growth Factor) regulates cell growth and myoblast proliferation. KGF (Keratinocyte Growth Factor) generates new keratinocytes, and CTGF (Connective Tissue Growth Factor) supports angiogenesis, cartilage regeneration and platelet adhesion.
Because Prizmah concentrates platelets while removing the red and white cells that contribute to inflammation and staining, the growth-factor payload it delivers is both potent and pure.
This article is derived from the official Prizmah clinical brochures and FAQ. It is for informational purposes and is not a substitute for professional medical advice.
